Clinical and Experimental Immunology

Antibody responses to Bordetella pertussis and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy- a prospective, observational cohort study from the UK

Rice T, Diavatopoulos D, Smits G, van Gageldonk P, Berbers G, van der Klis F, Vamvakas G, Donaldson B, Bouqueau M, Holder B*, Kampmann B* (*Joint last author)

Clinical and Experimental Immunology

The impact of timing of maternal influenza immunisation on infant antibody levels at birth.

Zhong Z, Haltalli M, Holder B, Rice T, Donaldson B, O'Driscoll M, Le-Doare K, Kampmann B, Tregoning JS



Journal for Extracellular Vesicles

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Thery C, (…) Holder B, (…) et al.


Macrophage- but not monocyte-derived extracellular vesicles induce placental pro-inflammatory response

Rice TF, Donaldson B, Bouqueau M, Kampmann B, Holder B.

PLoS Pathogens

Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome.

Szymula A, Palermo RD, Groves IJ, Ba Abdullah M, Holder B and White RE.



Clinical and Experimental Immunology

Immunosuppressive drugs affect IFN-gamma and PD1 kinetics in patients with newly diagnosed autoimmune hepatitis.

Grant CR, Holder B, Liberal R, Heneghan M, Ma Y, Mieli-Vergani G, Vergani D, Longhi MS.

Frontiers in Immunology

Factors Affecting the FcRn-Mediated Transplacental Transfer of Antibodies and Implications for Vaccination in Pregnancy

Wilcox CR, Holder B, Jones CE.




Macrophage exosomes induce placental inflammatory cytokines: a novel mode of maternal-placental messaging.

Holder B*, Jones T, Sancho Shimizu V, Rice TF, Donaldson B, Bouqueau M, Forbes K, Kampmann B




What determines uptake of pertussis vaccine in pregnancy? 

Donaldson B, Jain P, Holder BS, Lindsay, Regan L, Kampmann B.


In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression. 

Liberal R, Grant CR, Holder BS, Cardone J, Martinez-Llordella M, Ma Y, Heneghan MA, Mieli-Vergani G, Vergani D, Longhi MS.



Journal of Autoimmunity​

Retinoic acid stabilizes antigen-specific regulatory T-cell function in autoimmune hepatitis type 2.

Holder BS, Grant CR, Liberal R, Ma Y, Heneghan M, Mieli-Vergani G, Vergani D, Longhi MS.


Dysfunctional CD39POS regulatory T cells and aberrant control of T helper type 17 cells in autoimmune hepatitis. 

Grant CR, Liberal R, Holder BS, Cardone J, Ma Y, Robson SC, Mieli-Vergani G, Vergani D, Longhi MS.



Journal of Immunological Methods

Optimisation of a functional mycobacterial growth-inhibition  assay to improve its suitability for infant TB vaccine studies.

Burl S, Holder BS, Lo BK, Kampmann B.




The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/Tim-3 pathway.

Liberal R, Grant CR, Holder B, Ma Y, Mieli-Vergani G, Vergani D.​


Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1.

Holder BS, Tower CL., Forbes, K., Mulla, M. J., Aplin, J. D. and Abrahams, V. M. 


Inhibition of IL-17 promotes differentiation of CD25(-) cells into stable T regulatory cells in patients with autoimmune hepatitis.

Longhi MS, Liberal R, Holder B, Robson SC, Ma Y, Mieli-Vergani G, Vergani D.


Synctyin 1 in the human placenta.

Holder BS, Tower CL, Abrahams VM, Aplin JD.

Biology of Reproduction

Heightened pro-inflammatory effect of preeclamptic placental microvesicles on peripheral blood mononuclear cells in humans.

Holder BS, Tower CL, Jones CJ, Aplin JD and Abrahams VM.




Epstein-Barr virus, but not cytomegalovirus is associated with reduced vaccine antibody responses in Gambian infants.

Holder B, Miles DJC, Kaye S, Crozier S, Duah NO, Roberts E, Ojuola O, Palmero MS, Touray ES, Waight P, Cotton M, Rowland-Jones S, van der Sande M, Whittle H.




Cytomegalovirus infection induces T-cell differentiation without impairing antigen-specific responses in Gambian infants.

Miles DJC, Sanneh M, Holder B, Crozier S, Nyamweya S, Touray ES, Palmero MS, Zaman SMA, Rowland-Jones S, van der Sande M, and Whittle H.  


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